Best NMN Supplements-The Top 4 Natural Products In 2023

NMN, or nicotinamide mononucleotide, is a natural compound generating a ton of buzz in the health and wellness world. Many anti-aging and longevity experts have praised the potential benefits of supplementing with NMN. That’s why we’re here to rank and review the best NMN supplements on the market in 2023.

NMN is a precursor to an essential life-giving molecule called NAD+, or nicotinamide adenine dinucleotide. In other words, through complex chemical reactions, the body naturally converts NMN to NAD+, a coenzyme found in all living cells. NAD+ is critical for many biological processes and overall wellness on a cellular level.

Adequate NAD+ is necessary for:

Repairing Damaged DNA

Regenerating Healthy Cells

Reducing Oxidative Stress

Proper Gene Expression

Converting Food Into Energy

The human body synthesizes most of our NMN stores, while more negligible and generally inconsequential amounts can be consumed dietarily in foods like broccoli, cabbage, or edamame.

Yet, as we age, our bodies synthesize NMN less efficiently. In time, this will lead to a steep decline in NAD+ levels, resulting in potentially devastating cellular degradation. A study of human skin cells concluded that by the time most people reach middle age, NAD+ levels decline by 50&#37 or more.[1]

Researchers performing that study noted, “NAD+ depletion may play a major role in the aging process, by limiting energy production, DNA repair and genomic signaling”. Since then, more professionals have come to agree NAD+ may be crucial to anti-aging technology, and NMN supplements can be a viable way to help restore NAD+ levels.

Now you may ask yourself, why not just ingest NAD+ directly? The problem is NAD+ is too big of a molecule to be absorbed by the human body. It’s likely to pass through the digestive system and be expelled. Many scientists believe NMN supplementation could be the answer to this longstanding and puzzling problem.

In this article, we’ll give you all pertinent information on the 4 best NMN supplements available and help you to understand how they could improve your quality of life.

Best NMN Supplements—Our Picks

We’ve pounded the pavement and put in the work to determine which NMN supplements could be considered truly elite. As a result, we’ve put together a list of 4 high-quality products that may provide significant benefits for anti-aging and longevity.

The 4 best NMN supplements are:

1 GenF20 Liposomal NMN+—Best For Reliable Results

2 Double Wood NMN—Best For Energy Metabolism

3 Cymbiotika NMN—Best For Antioxidant Activity

4 Youth & Earth NMN—Best For UK-Based Residents

If you’re interested in incorporating cutting-edge wellness technology into your life, these are the best NMN supplements to help you do so.

We like GenF20 Liposomal NMN+ best because it uses enhanced absorption technology to deliver purified NMN with the highest bioavailability. Still, all of these products may offer some advantages for anti-aging and longevity.

Identifying The Best NMN Supplements

Since the recent explosion of interest in NMN and NAD+, scores of supplements have entered the market. While some of these products (like those on this list) are high-end, most are not.

Many manufacturers cut corners to make an extra buck. They have no problem providing a subpar product while completely shortchanging users. It can be tricky to weed out the good NMN supplements from the bad.

However, there are a few key characteristics to look at when determining the overall quality of an NMN supplement.

To find the best NMN supplements, it’s important to consider:

NMN Quality—Not all NMN supplements contain authentic or pure NMN. Highly pure NMN is cost-prohibitive for manufacturers, so many may use low-quality NMN or no NMN. However, higher-purity NMN and an optimal serving size should yield more efficient results. Ideally, 95&#37 pure or greater NMN will be best.

Bioavailability—NMN is notoriously difficult for the body to absorb. This is another reason why consuming NMN via dietary means is difficult. The elite NMN supplements should have some form of enhanced absorption technology or use a bioavailability enhancer to promote better absorption.

Brand Reliability—Once some reliable data began to emerge demonstrating the benefits of NMN supplementation, many “fly by night” supplement manufacturers began to emerge. These companies were just trying to cash in quickly while selling ineffective products. Finding an NMN supplement built by a reliable brand is important for results.

Manufacturing Practices—Many companies opt to build their supplements in low-income countries, where regulations and safety standards are lesser. Ideally, you’d want to find a supplement manufactured in cGMP-certified facilities in the USA. This will help to ensure product consistency and safety.

Money-Back Guarantee—The best NMN supplements, or any health supplement for that matter, should offer a money-back guarantee. Top-notch manufacturers give no strings attached guarantees. This provides consumer protection and shows the company has the ultimate confidence in its product.

Fortunately, we considered all these factors when compiling this list of the best NMN supplements. However, should you decide to shop around, keeping these factors in mind is vital.

It’s important to note NMN supplements aren’t designed to make severe health issues better. If you’re dealing with a serious health problem, consult a physician before using any supplement. 

Now that we’ve covered that, it’s time to take a closer look at the best NMN supplements out there.

1 GenF20 Liposomal NMN+—Best For Reliable Results

The winner of the best NMN supplement is the reliable, highly pure formula, GenF20 Liposomal NMN+.

This supplement encases its high-quality NMN inside an innocuous fatty substance called liposomal. This form of enhanced absorption technology protects the fragile NMN compounds from stomach acid. That way, the body can absorb more of the molecules.

As a result, Liposomal NMN can yield significantly greater results than other forms of NMN. And it comes with no reported negative side effects.

GenF20 has been building elite anti-aging and longevity supplements in the USA for over 2 decades.  And this product absolutely lives up to the lofty expectations they’ve set.

The supplement requires an easy-to-swallow single daily pill and could show noticeable results in approximately 4-6 weeks.

NMN Quality & Bioavailability Status

GenF20 Liposomal NMN+ contains pure β-Nicotinamide Mononucleotide 98&#37. This clean form of NMN provides excellent outcomes with no known downsides. The truth is, it’s likely the purest form of NMN you’ll find almost anywhere. The manufacturer can even send a certificate of authenticity to prove it.

Additionally, GenF20 Liposomal NMN+ delivers superior bioavailability thanks to the microscopic lipids that protect each serving of β-Nicotinamide Mononucleotide 98&#37 from corrosive stomach acid.

And Liposomal NMN+ contains absolutely no fillers or additives.

In fact, this product is:








It’s as clear as day GenF20 Liposomal NMN+ is the best NMN supplement on the market due to the high-quality NMN, enhanced absorption technology, and lack of fillers or additives.

Potential Benefits

GenF20 Liposomal NMN+ can offer superior benefits to users looking to improve upon common health pitfalls related to aging.

GenF20 Liposomal NMN+ could help to:

Boost Daily Energy

Support Physical Strength

Enhance Libido

Improve Mood & Mindset

Promote Cognitive Function

If you’re suffering at the hands of father time, like so many of us are, GenF20 Liposomal NMN+ is designed to help you restore some of that fleeting youthful vitality.

Manufacturing & Money-Back Guarantee

GenF20 Liposomal NMN+ is manufactured in cGMP-certified facilities in the USA. This means the manufacturer adheres to the highest safety standards in the industry.

And this supplement comes with a 67-day money-back guarantee. You can even use some or all of your supply and return it if it doesn’t work for you. At that time, you’ll receive a refund of the purchase price.

Pros & Cons

There’s a lot to like about GenF20 Liposomal NMN+. It’s the best NMN supplement, after all. But let’s check the pros and cons.


Highly Pure NMN

Increased Bioavailability

Reputable Brand

Excellent Manufacturing Practices

Elite Money-Back Guarantee

Free Shipping Available In The USA


Can Only Be Purchased Online

GenF20 Liposomal NMN+ uses an impressive formula for improving NAD+ levels. It’s simply terrific. The only downside is you’ll only be able to buy it online.

Where To Purchase

Head directly to the official product homepage for the best customer experience.

2 Double Wood NMN—Best For Energy Metabolism

Coming in 2nd on this ranking of the best NMN supplements is Double Wood NMN.

Manufactured in cGMP-certified facilities in the USA, Double Wood has shown promising results in increasing energy metabolism for middle-aged users.

This is a common outcome related to increased NDA+ levels.

NMN Quality & Bioavailability Status

Double Wood NMN contains a healthy serving of NMN molecules. However, the purity of the NMN isn’t precisely clear based on the latest company data.

The formula doesn’t incorporate any form of enhanced absorption technology or a bioavailability enhancer into its ingredient lineup.

Though Double Wood NMN is:




Built With A Proper NMN Quantity

While Double Wood NMN lacks some elite characteristics, evidence suggests it could be a reliable NMN supplement, especially for increasing energy levels. 

This product requires taking 2 capsules per day for the best results.

Potential Benefits

The serving of NMN in Double Wood NMN should help to enhance NAD+ resulting in energy gains and potentially other benefits.

Double Wood NMN could help to:

Increase Energy

Upgrade Stamina

Improve Sleep Quality

Support Graceful Aging

Double Wood NMN is undoubtedly better than most NMN supplements out there. It could help to reverse some troubling outcomes of aging for most people.

Manufacturing & Money-Back Guarantee

As stated above, Double Wood NMN is manufactured in cGMP-certified facilities in the USA. The company’s headquarters are located in Pennsylvania.

Double Wood Supplements also offers a 30-day money-back guarantee. You’ll have 30 days from the delivery date to apply for a refund.

Pros & Cons

Double Wood NMN has several admirable qualities that make it one of the best NMN supplements. We’ll run down the pros and cons.


Research-Supported Quantity Of NMN

Excellent Manufacturing Practices

Good Money-Back Guarantee

Free Shipping Available In The USA


Unclear NMN Purity

No Bioavailability Enhancer

Only Available Online

Double Wood NMN may support NAD+ increases. Multiple user reviews would say the same. However, it does lack some key characteristics to be considered elite. 

Where To Purchase

Click on the official Double Wood Supplements webpage for more information.

3 Cymbiotika NMN—Best For Antioxidant Activity

Cymbiotika NMN takes number 3 on our list of the best NMN supplements.

Designed and manufactured in the USA, Cymbiotika NMN provides both NMN support and several potent antioxidants.

This formula could help to reduce oxidative stress even more than just increased NAD+ could do alone.

NMN Quality & Bioavailability Status

Cymbiotika NMN contains a large serving of NMN. However, the purity of the NMN is unclear, according to the manufacturer.

There is no bioavailability enhancer present in the Cymbiotika NMN formula, either.

That said, it does contain several added compounds that act as potent antioxidants, which may further reduce oxidative stress (something increased NAD+ can also do).

Those ingredients are:


Green Tea Extract


Green Coffee Bean

These additional compounds could enhance some effects of NAD+ increases and be ideal for those with high oxidate stress measurements.

Cymbiotika NMN requires users to take 2 pills per day.

Potential Benefits

The robust serving of NMN in this formula may significantly contribute to boosted NAD+ levels. And the presence of several antioxidants brings added elements.

Cymbiotika NMN could help to:

Reduce Oxidative Stress

Boost Daily Energy

Slow Early Aging

Improve Cellular Wellness

Cymbiotika NMN belongs in the conversation with the best NMN supplements. The unique ingredients might make for several distinct benefits.

Manufacturing & Money-Back Guarantee

Cymbiotika NMN is manufactured in cGMP-certified facilities in the USA. The relatively new company, founded in 2017, is based out of California.

They offer a 30-day money-back guarantee. You can return any unopened bottles up to 30 days after the delivery date. However, no opened bottle will be refunded.

Pros & Cons

Cymbiotika NMN may offer some notable advantages, especially for reducing oxidative stress. Let’s discuss the positives and negatives.


Large Serving Of NMN

Several Antioxidants

Excellent Manufacturing Practices

May Further Reduce Oxidative Stress


Unclear NMN Purity

No Bioavailability Enhancer

No Refund On Opened Bottles

Although untested for purity, the large serving of NMN and the potent antioxidants are definite positives. However, there could be some improvements made to the formula.

Where To Purchase

Head to the official Cymbiotika NMN website for the best deal.

4 Youth & Earth NMN—Best For UK-Based Users

Youth & Earth NMN comes in 4th among the best NMN supplements.

Developed and headquartered in the UK, Youth & Earth NMN contains a hefty dose of NMN to help restore NAD+ levels naturally.

The supplement could be ideal for UK-based users due to low shipping costs and better customer service in the manufacturer’s home country.

NMN Quality & Bioavailability Status

Youth & Earth NMN is comprised of a single ingredient, a massive serving of NMN. The serving size is excellent, yet the purity of the NMN is somewhat opaque. As far as we can tell, the manufacturer claims high purity but doesn’t provide authentication.

Youth & Earth NMN also promotes gastro-resistant vegan capsules, but it`s unclear exactly how effective they are for enhanced absorption.

However, the giant but healthy serving size of NMN definitely puts Youth & Earth NMN in the running with the best NMN supplements.

The manufacturer recommends taking 2 pills a day for the best results.

Potential Benefits

The hefty portion of NMN present in Youth & Earth NMN should provide ample benefits for NAD+ production. This could promote several anti-aging and longevity advantages.

Youth & Earth NMN could help to:

Promote Cell Vitality

Repair Cell Damage

Improve Cognitive Function

Boost Energy

If you’re based in the UK, Youth & Earth NMN could be an affordable, reliable option to get your NAD+ levels where they need to be.

Manufacturing & Money-Back Guarantee

As stated, Youth & Earth NMN is manufactured in the UK. However, the company does adhere to cGMP policies set forth by the FDA.

They offer a 60-day money-back guarantee. The company will reimburse you the purchase price for all bottles, opened and unopened.

Shipping costs may be higher for individuals located outside of the UK.

Pros & Cons

Youth & Earth NMN offers a solid serving of NMN, but it’s not a perfect product. So let’s check it out.


Hefty Serving Of NMN


Good Manufacturing Practices

Solid Money-Back Guarantee


Unclear NMN Purity

Lacking Advanced Absorption Technology

Larger Shipping Rates Outside Of The UK

There’s quite a bit to like about Youth & Earth NMN, especially with its quantity of NMN. Yet, this supplement has some blemishes that keep it from the top of the list.

Where To Purchase

Learn more at the Youth & Earth NMN official homepage.

Best NMN Supplements—Parting Words

Getting older can bring many unwanted troubles. Evidence has recently emerged showing NAD+ decline is a big reason for this. But it doesn’t have to be.

The best NMN supplements could help you to produce more NAD+, live life fully, and subsequently age more like a fine wine. Choosing one of the best NMN supplements on our list can help optimize your wellness now, and for a long time to come. So, what are you waiting for?


Disclaimer: The views and opinions expressed in this sponsored article are those of the sponsor/author/agency and do not represent the stand and views of Mid-Day Group.Mid-Day Group disclaims any and all liability to any party, company or product for any direct, indirect, implied, punitive, special, incidental or consequential damages arising directly or indirectly from the use of this content.